Invention Grant
- Patent Title: Quinolizidinone M1 receptor positive allosteric modulators
- Patent Title (中): 喹诺酮酮M1受体阳性变构调节剂
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Application No.: US12812907Application Date: 2009-01-15
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Publication No.: US08273737B2Publication Date: 2012-09-25
- Inventor: Scott D. Kuduk , Ronald K. Chang
- Applicant: Scott D. Kuduk , Ronald K. Chang
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sylvia A. Ayler; Gerard M. Devlin
- International Application: PCT/US2009/031032 WO 20090115
- International Announcement: WO2009/094279 WO 20090730
- Main IPC: A01N43/62
- IPC: A01N43/62 ; A61K31/55
Abstract:
The present invention is directed to compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
Public/Granted literature
- US20110112077A1 Quinolizidinone m1 Receptor Positive Allosteric Modulators Public/Granted day:2011-05-12
Information query
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