The USB AC adapter with removable USB vehicle power adapter comprises of a housing with a slot that holds a removable vehicle power adapter. The housing has an alternating current plug adapted to be insertable into an alternating current source. The housing further encloses a universal serial bus. Power conversion circuits are enclosed in the housing to convert the 110V alternating current to both 5V and 12V direct currents. The 5V direct current is directed through the universal serial bus in the housing. The 12V direct current is directed to the slot that holds the removable vehicle power adapter. The removable vehicle power adapter is adapted to be removable from the housing and insertable into a vehicle's cigarette lighter socket and converts the 12V from the vehicle's direct current power supply to 5V direct current output through a universal serial bus.