中科微点-全球专利检索

  1. Login
  2. Sign Up
Invention Grant
US08277779B2 Compositions useful for reducing nephrotoxicity and methods of use thereof 有权
用于减少肾毒性的组合物及其使用方法

  • Patent Title: Compositions useful for reducing nephrotoxicity and methods of use thereof
  • Patent Title (中): 用于减少肾毒性的组合物及其使用方法
  • Application No.: US12641708
    Application Date: 2009-12-18
  • Publication No.: US08277779B2
    Publication Date: 2012-10-02
  • Inventor: Vernon D. Rowe
  • Applicant: Vernon D. Rowe
  • Agency: Akerman Senterfitt LLP
  • Main IPC: A61K49/04
  • IPC: A61K49/04
Compositions useful for reducing nephrotoxicity and methods of use thereof
Abstract:
The present invention provides compositions and methods to reduce renal damage caused by nephrotoxic drugs. The invention provides compositions comprising an anionically substituted cyclodextrin, a nephrotoxic drug and a pharmaceutically acceptable carrier, where the cyclodextrin is present in an amount effective for substantially inhibiting the nephrotoxic effect of the drug.
Abstract(Chinese):

本发明提供减少由肾毒性药物引起的肾损伤的组合物和方法。 本发明提供了包含阴离子取代的环糊精，肾毒性药物和药学上可接受的载体的组合物，其中环糊精的存在量对于显着抑制药物的肾毒性作用是有效的。

Public/Granted literature
Information query
Espacenet
Patent Agency Ranking
0/0