Invention Grant
- Patent Title: Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids
- Patent Title (中): 使用糖脂稳定基于脂质的佐剂制剂的组合物和方法
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Application No.: US12784821Application Date: 2010-05-21
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Publication No.: US08277823B2Publication Date: 2012-10-02
- Inventor: Jesper Davidsen , Peter Andersen , Ida Rosenkrands
- Applicant: Jesper Davidsen , Peter Andersen , Ida Rosenkrands
- Applicant Address: DK Copenhagen S
- Assignee: Statens Serum Institut
- Current Assignee: Statens Serum Institut
- Current Assignee Address: DK Copenhagen S
- Agency: Howson & Howson LLP
- Priority: DK200401070 20040707
- Main IPC: A61K45/00
- IPC: A61K45/00 ; A61K51/00 ; A61K47/44
Abstract:
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular the invention relates to vaccines with adjuvants in aqueous media for immunization, where the final product is stable.
Public/Granted literature
- US20100226975A1 Compositions and Methods for Stabilizing Lipid Based Adjuvant Formulations Using Glycolipids Public/Granted day:2010-09-09
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