Invention Grant
US08278104B2 Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
有权
用Oct3 / 4，Klf4和Sox2产生的诱导多能干细胞
- Patent Title: Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
- Patent Title (中): 用Oct3 / 4，Klf4和Sox2产生的诱导多能干细胞
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Application No.: US12213035Application Date: 2008-06-13
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Publication No.: US08278104B2Publication Date: 2012-10-02
- Inventor: Shinya Yamanaka , Kazutoshi Takahashi , Keisuke Okita
- Applicant: Shinya Yamanaka , Kazutoshi Takahashi , Keisuke Okita
- Applicant Address: JP Kyoto
- Assignee: Kyoto University
- Current Assignee: Kyoto University
- Current Assignee Address: JP Kyoto
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: JP2005-359537 20051213
- Main IPC: C12N5/02
- IPC: C12N5/02 ; C12N15/00
Abstract:
The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.
Public/Granted literature
- US20090047263A1 Nuclear reprogramming factor and induced pluripotent stem cells Public/Granted day:2009-02-19
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