Invention Grant
US08278275B2 Method to enhance hemodynamic stability using oxygen carrying compositions
有权
使用携氧组合物增强血液动力学稳定性的方法
- Patent Title: Method to enhance hemodynamic stability using oxygen carrying compositions
- Patent Title (中): 使用携氧组合物增强血液动力学稳定性的方法
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Application No.: US12623760Application Date: 2009-11-23
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Publication No.: US08278275B2Publication Date: 2012-10-02
- Inventor: Robert M. Winslow , Kim D. Vandegriff
- Applicant: Robert M. Winslow , Kim D. Vandegriff
- Applicant Address: US CA San Diego
- Assignee: Sangart, Inc.
- Current Assignee: Sangart, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Gordon & Rees LLP
- Agent Laurie A. Axford
- Main IPC: A61K38/42
- IPC: A61K38/42 ; A61P9/00
Abstract:
The present invention relates to methods for enhancing the hemodynamic stability of an individual undergoing surgery by administering a composition comprising a hemoglobin-based oxygen carrier. In one embodiment, the present invention relates to the use of polyalkylene oxide modified hemoglobins with reduced cooperativity and a high oxygen affinity to enhance oxygen offloading as a preventative measure to avoid hemodynamic stability-related complications during surgery.
Public/Granted literature
- US20100087361A1 METHOD TO ENHANCE HEMODYNAMIC STABILITY USING OXYGEN CARRYING COMPOSITIONS Public/Granted day:2010-04-08
Information query
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