Invention Grant
- Patent Title: Antagonists of the bradykinin B1 receptor
- Patent Title (中): 缓激肽B1受体的拮抗剂
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Application No.: US12082219Application Date: 2008-04-08
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Publication No.: US08278280B2Publication Date: 2012-10-02
- Inventor: Gordon Ng , Yue-Sheng Li , Colin V. Gegg , Benny C. Askew, Jr. , Thomas Storz , Yuelie Lu , Derin C. D'Amico , Mark A. Jarosinski , Chuan-Fa Liu , Qi Huang
- Applicant: Gordon Ng , Yue-Sheng Li , Colin V. Gegg , Benny C. Askew, Jr. , Thomas Storz , Yuelie Lu , Derin C. D'Amico , Mark A. Jarosinski , Chuan-Fa Liu , Qi Huang
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Nisan A. Steinberg
- Main IPC: C07K7/18
- IPC: C07K7/18

Abstract:
The present invention relates to composition of matter involving bradykinin B1 receptor antagonist peptides conjugated to a multivalent vehicle, including peptides conjugated to multivalent PEG. These compositions can be used as therapeutics or prophylactics against diseases or conditions, such as inflammation or pain, linked to the bradykinin B1 receptor.
Public/Granted literature
- US20090137452A1 Antagonists of the bradykinin B1 receptor Public/Granted day:2009-05-28
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