Invention Grant
US08278294B2 Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase
有权
取代的异喹啉和异喹啉酮衍生物作为Rho激酶的抑制剂
- Patent Title: Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase
- Patent Title (中): 取代的异喹啉和异喹啉酮衍生物作为Rho激酶的抑制剂
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Application No.: US12487403Application Date: 2009-06-18
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Publication No.: US08278294B2Publication Date: 2012-10-02
- Inventor: Oliver Plettenburg , Armin Hofmeister , Joachim Brendel , Matthias Lohn
- Applicant: Oliver Plettenburg , Armin Hofmeister , Joachim Brendel , Matthias Lohn
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Agent Thomas Loeschner
- Priority: EP06026898 20061227
- Main IPC: A61K31/397
- IPC: A61K31/397
Abstract:
The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
Public/Granted literature
- US20100063025A1 Substituted isoquinoline and isoquinolinone derivatives as inhibitors of RHO-Kinase Public/Granted day:2010-03-11
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