Invention Grant
- Patent Title: Substituted piperidines as CCR3 antagonists
- Patent Title (中): 取代的哌啶作为CCR3拮抗剂
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Application No.: US12727318Application Date: 2010-03-19
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Publication No.: US08278302B2Publication Date: 2012-10-02
- Inventor: Marc Grundl , Horst Dollinger , Riccardo Giovannini , Christoph Hoenke , Matthias Hoffmann , Jan Kriegl , Domnic Martyres , Georg Rast , Peter Seither
- Applicant: Marc Grundl , Horst Dollinger , Riccardo Giovannini , Christoph Hoenke , Matthias Hoffmann , Jan Kriegl , Domnic Martyres , Georg Rast , Peter Seither
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Mary-Ellen M. Devlin
- Priority: EP09157653 20090408; EP09174917 20091103
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/445 ; C07D413/04 ; C07D413/14 ; C07D401/04 ; C07D401/14
Abstract:
Object of the present invention are novel substituted compounds of the formula 1, wherein A, R1, R2, R3 and R4 are defined as in the description. Another object of the present invention is to provide antagonists of CCR3, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20100261687A1 SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS Public/Granted day:2010-10-14
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