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US08278422B2 Antibodies that specifically bind beta-like glycoprotein hormone polypeptides and heterodimers thereof 失效
特异性结合β样糖蛋白激素多肽及其异源二聚体的抗体

  • Patent Title: Antibodies that specifically bind beta-like glycoprotein hormone polypeptides and heterodimers thereof
  • Patent Title (中): 特异性结合β样糖蛋白激素多肽及其异源二聚体的抗体
  • Application No.: US12816475
    Application Date: 2010-06-16
  • Publication No.: US08278422B2
    Publication Date: 2012-10-02
  • Inventor: Christopher J. R. Paszty
  • Applicant: Christopher J. R. Paszty
  • Agent John A. Lamerdin
  • Main IPC: C07K16/26
  • IPC: C07K16/26 ;  C07K14/59
Antibodies that specifically bind beta-like glycoprotein hormone polypeptides and heterodimers thereof
Abstract:
Novel β10 polypeptides and heterodimers thereof, and nucleic acid molecules encoding the same are disclosed. The invention also provides vectors, host cells, selective binding agents, and methods for producing β10 polypeptides and heterodimeric forms thereof, specifically α2/β10. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with β10 polypeptides and α2/β10 heterodimers or their respective binding agents.
Abstract(Chinese):

公开了10种多肽及其异源二聚体及其编码的核酸分子。 本发明还提供了载体，宿主细胞，选择性结合剂，以及用于产生10种多肽及其异二聚体形式的方法，特别是α2 / bgr。 还提供了用于治疗，诊断，改善或预防具有10种多肽和α2/ bgr10异源二聚体或其各自结合剂的疾病的方法。

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