Invention Grant
- Patent Title: N-pyrazole A2A receptor agonists
- Patent Title (中): N-吡唑A2A受体激动剂
-
Application No.: US12968110Application Date: 2010-12-14
-
Publication No.: US08278435B2Publication Date: 2012-10-02
- Inventor: Jeff A. Zablocki , Elfatih O. Elzein , Venkata Palle , Luiz Belardinelli
- Applicant: Jeff A. Zablocki , Elfatih O. Elzein , Venkata Palle , Luiz Belardinelli
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agency: Foley & Lardner LLP
- Main IPC: C07H19/00
- IPC: C07H19/00 ; C07H19/167
Abstract:
The present disclosure provides a process for the preparation of 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A2A adenosine receptor, compositions comprising these compounds, and methods for using these compounds to stimulate mammalian coronary vasodilation for imaging the heart.
Public/Granted literature
- US20110144320A1 N-PYRAZOLE A2A RECEPTOR AGONISTS Public/Granted day:2011-06-16
Information query
