Invention Grant
US08278452B2 Heterocyclic compounds and compositions as c-kit and PDGFR kinase inhibitors
失效
杂环化合物和组合物作为c-kit和PDGFR激酶抑制剂
- Patent Title: Heterocyclic compounds and compositions as c-kit and PDGFR kinase inhibitors
- Patent Title (中): 杂环化合物和组合物作为c-kit和PDGFR激酶抑制剂
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Application No.: US12918801Application Date: 2009-02-20
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Publication No.: US08278452B2Publication Date: 2012-10-02
- Inventor: Donatella Chianelli , Xiaolin Li , Xiaodong Liu , Jon Loren , Valentina Molteni , Juliet Nabakka , Vince Yeh
- Applicant: Donatella Chianelli , Xiaolin Li , Xiaodong Liu , Jon Loren , Valentina Molteni , Juliet Nabakka , Vince Yeh
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Daniel E. Raymond
- International Application: PCT/US2009/034778 WO 20090220
- International Announcement: WO2009/105712 WO 20090827
- Main IPC: C07D471/02
- IPC: C07D471/02
Abstract:
The invention provides a novel class of compounds of Formula I: (I) pharmaceutical compositions comprising such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases.
Public/Granted literature
- US20110183997A1 HETEROCYCLIC COMPOUNDS AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS Public/Granted day:2011-07-28
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