Invention Grant
US08278469B2 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives, method of production thereof and use thereof for the treatment of diseases
有权
17-羟基-17-五氟乙基 - 雌-4,9（10） - 二-11-芳基衍生物，其制备方法及其用于治疗疾病的用途
- Patent Title: 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives, method of production thereof and use thereof for the treatment of diseases
- Patent Title (中): 17-羟基-17-五氟乙基 - 雌-4,9（10） - 二-11-芳基衍生物，其制备方法及其用于治疗疾病的用途
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Application No.: US13324912Application Date: 2011-12-13
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Publication No.: US08278469B2Publication Date: 2012-10-02
- Inventor: Wolfgang Schwede , Ulrich Klar , Carsten Moller , Andrea Rotgeri , Wilhelm Bone
- Applicant: Wolfgang Schwede , Ulrich Klar , Carsten Moller , Andrea Rotgeri , Wilhelm Bone
- Applicant Address: DE Berlin
- Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee Address: DE Berlin
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102009034362 20090720
- Main IPC: C07J1/00
- IPC: C07J1/00 ; A61K31/56
Abstract:
The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of Formula I with progesterone antagonizing action and method of production thereof, use thereof for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular of fibroids of the uterus (myomas, uterine leiomyoma), endometriosis, heavy menstrual bleeds, meningiomas, hormone-dependent breast cancers and complaints associated with the menopause or for fertility control and emergency contraception.
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