Communication to or from a nanodevice is provided with a nanostructure-based antenna, preferably formed from, but not limited to, a single wall nanotube (SWNT). Other nanostructure-based antennas include double walled nanotubes, semiconducting nanowires, metal nanowires and the like. The use of a nanostructure-based antenna eliminates the need to provide a physical communicative connection to the nanodevice, while at the same time allowing communication between the nanodevice and other nanodevices or outside systems, i.e., systems larger than nanoscale such as those formed from semiconductor fabrication processes such as CMOS, GaAs, bipolar processes and the like.