A liquid crystal display panel includes a sub-pixel array, a plurality of scan lines, and a plurality of data lines. The sub-pixel array has a plurality of sub-pixels arranged in array. Any two neighboring scan lines of the scan lines and a row of the sub-pixels disposed between the two neighboring scan liens are electrically connected. The sub-pixels arranged in odd rows are electrically connected to the odd-numbered data lines, and the sub-pixels arranged in even rows are electrically connected to the even-numbered data lines. Thus, the liquid crystal display panel is able to reduce mura phenomenon through the above-mentioned layout. A driving method of the above-mentioned liquid crystal display panel is also provided.