A double data rate bus system includes a host-network interface card configuration wherein the host is configured to recognize the network interface card to establish a double data rate bus between the host and the network interface card. The host is configured to generate a plurality of generic data frame queues. Each of the generic data frame queues is configured to receive and to transmit generic data frames via the double data rate bus. The network interface card is configured to transmit a plurality of dynamic memory access read requests to the host via the double data rate bus. The host is configured to allow each of the plurality of dynamic memory access read requests to remain pending prior to responding to any one of the plurality of dynamic memory access read requests.