Invention Grant
- Patent Title: PFKFB4 inhibitors and methods of using the same
- Patent Title (中): PFKFB4抑制剂及其使用方法
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Application No.: US12761773Application Date: 2010-04-16
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Publication No.: US08283332B2Publication Date: 2012-10-09
- Inventor: Sucheta Telang , Jason Chesney
- Applicant: Sucheta Telang , Jason Chesney
- Applicant Address: US KY Louisville
- Assignee: University of Louisville Research Foundation, Inc.
- Current Assignee: University of Louisville Research Foundation, Inc.
- Current Assignee Address: US KY Louisville
- Agency: Dinsmore & Shohl LLP
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
Methods of reducing expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) and methods of treating a cancer in a cell are provided, the methods including contacting a cell with an effective amount of a PFKFB4 inhibitor. Short hairpin RNA (shRNA) and small interfering RNA (siRNA) inhibitors of PFKFB4 and their methods of use are also provided.
Public/Granted literature
- US20100267815A1 PFKFB4 Inhibitors And Methods Of Using The Same Public/Granted day:2010-10-21
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