Invention Grant
US08283450B2 Human monoclonal antibody human CD134 (OX40) and methods of making and using same
有权
人单克隆抗体人CD134(OX40)及其制备和使用方法
- Patent Title: Human monoclonal antibody human CD134 (OX40) and methods of making and using same
- Patent Title (中): 人单克隆抗体人CD134(OX40)及其制备和使用方法
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Application No.: US12087436Application Date: 2006-11-27
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Publication No.: US08283450B2Publication Date: 2012-10-09
- Inventor: Shinichiro Kato , Rachel Soloff Nugent , Hitoshi Yoshida , Michael Croft
- Applicant: Shinichiro Kato , Rachel Soloff Nugent , Hitoshi Yoshida , Michael Croft
- Applicant Address: JP Tokyo US CA La Jolla
- Assignee: Kyowa Hakko Kirin Co., Ltd.,La Jolla Institute for Allergy and Immunology
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.,La Jolla Institute for Allergy and Immunology
- Current Assignee Address: JP Tokyo US CA La Jolla
- Agency: Pillsbury Winthrop Shaw Pittman, LLP
- International Application: PCT/US2006/045522 WO 20061127
- International Announcement: WO2007/062245 WO 20070531
- Main IPC: C12P21/08
- IPC: C12P21/08

Abstract:
The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.
Public/Granted literature
- US20100196359A1 Human Monoclonal Antibody Human CD134 (Ox40) and Methods of Making and Using Same Public/Granted day:2010-08-05
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