Invention Grant
- Patent Title: CXCR2 inhibitors
- Patent Title (中): CXCR2抑制剂
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Application No.: US13079522Application Date: 2011-04-04
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Publication No.: US08283479B2Publication Date: 2012-10-09
- Inventor: Stephanie Hachtel , Juergen Dedio , Holger Heitsch , Werngard Czechtizky , Sven Grueneberg , Stephen J. Shimshock , Raymond W. Kosley, Jr. , Carolina L. Lanter , Hui Li , Rosy Sher , Aleksandra Weichsel
- Applicant: Stephanie Hachtel , Juergen Dedio , Holger Heitsch , Werngard Czechtizky , Sven Grueneberg , Stephen J. Shimshock , Raymond W. Kosley, Jr. , Carolina L. Lanter , Hui Li , Rosy Sher , Aleksandra Weichsel
- Applicant Address: DE Frankfurt am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP04031009 20041230
- Main IPC: C07D333/66
- IPC: C07D333/66 ; C07D409/12 ; A61K31/44
Abstract:
The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
Public/Granted literature
- US20110184177A1 CXCR2 INHIBITORS Public/Granted day:2011-07-28
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