Invention Grant
- Patent Title: Transgenic mouse models of Aβ overexpression
- Patent Title (中): A＆bgr的转基因小鼠模型 过表达
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Application No.: US12209321Application Date: 2008-09-12
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Publication No.: US08283517B2Publication Date: 2012-10-09
- Inventor: Stephan Schilling , Holger Cynis , Hans-Ulrich Demuth , Wolfgang Jagla , Sigrid Graubner
- Applicant: Stephan Schilling , Holger Cynis , Hans-Ulrich Demuth , Wolfgang Jagla , Sigrid Graubner
- Applicant Address: DE Halle (Saale)
- Assignee: Probiodrug AG
- Current Assignee: Probiodrug AG
- Current Assignee Address: DE Halle (Saale)
- Agency: SNR Denton US LLP
- Main IPC: G01K33/00
- IPC: G01K33/00 ; A01K67/033 ; A01K67/027 ; C12N5/00
Abstract:
A transgenic non-human animal, in particular a transgenic mouse encoding Aβ peptide proteins, which have been implicated in Aβ peptide-related diseases. Cells and cell lines comprising transgenes encoding for Aβ peptide. Methods and compositions for evaluating agents that affect Aβ peptide, for use in compositions for the treatment of Aβ peptide-related diseases.
Public/Granted literature
- US20090098052A1 TRANSGENIC MICE Public/Granted day:2009-04-16
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