A rice hybrid designated XP754 is disclosed. The invention relates to the seeds of rice hybrid XP754, to the plants of rice hybrid XP754 and to methods for producing a rice plant produced by crossing the hybrid XP754 with itself or another rice plant. The invention further relates to hybrid rice seeds and plants produced by crossing the hybrid XP754 with another rice plant. This invention further relates to growing and producing blends of rice seeds comprised of seeds of rice hybrid XP754 with rice seed of one, two, three, four or more of another rice hybrid, rice variety or rice inbred.