Systems and methods to outsource service and support operations are disclosed. An example method disclosed herein includes electronically maintaining an inventory at an outsourced service and support partner (OSSP) without intervention by a separate manufacturing entity by ordering inventory items from a supplier separate from the manufacturing entity and the OSSP at a cost determined based on an amount of similar or substantially identical inventory items obtained separately by the manufacturing entity for manufacturing units, and using the inventory to at least one of service a unit returned to the OSSP by a customer or ship an inventory item from the OSSP to the customer in response to receiving an order notification from the manufacturing entity at the OSSP.