A system and method are described for storing and accessing data using a plurality of probabilistic data structures. In one embodiment, a plurality of probabilistic data structures are identified, each probabilistic data structure being associated with at least one other probabilistic data structure. The plurality of probabilistic data structures each correspond to a portion of a storage device storing a dataset. The dataset may include a plurality of values, such as a plurality of data blocks. A plurality of keys may be generated from the plurality of values, such as a plurality of fingerprints. Each key may be inserted into the probabilistic data structures which correspond to the portion of the storage device storing the value the key was generated from. The plurality of probabilistic data structures are stored in a memory and may be queried with an item to determine if the item exists in the plurality of probabilistic data structures.