Invention Grant
- Patent Title: Methods for making oxidation-resistant cross-linked polymeric materials
- Patent Title (中): 制造抗氧化交联聚合物材料的方法
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Application No.: US12522728Application Date: 2008-01-25
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Publication No.: US08293811B2Publication Date: 2012-10-23
- Inventor: Orthun K. Muratoglu , Edward T. Kopesky , Ebru Oral
- Applicant: Orthun K. Muratoglu , Edward T. Kopesky , Ebru Oral
- Applicant Address: US MA Boston US MA Boston
- Assignee: The General Hospital Corporation,Cambridge Polymer Group, Inc.
- Current Assignee: The General Hospital Corporation,Cambridge Polymer Group, Inc.
- Current Assignee Address: US MA Boston US MA Boston
- Agency: Perkins Coie LLP
- International Application: PCT/US2008/092047 WO 20080125
- International Announcement: WO2008/092047 WO 20080731
- Main IPC: C08F2/46
- IPC: C08F2/46 ; C08J3/28 ; A61F2/02 ; A61F2/30 ; A61L27/50 ; A61L27/16 ; C08L23/06 ; C08K5/1545
Abstract:
The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (α-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (α-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.
Public/Granted literature
- US20100190882A1 METHODS FOR MAKING OXIDATION-RESISTANT CROSS-LINKED POLYMERIC MATERIALS Public/Granted day:2010-07-29
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