An audio processing circuit includes a crosstalk cancellation circuit that is advantageously simplified for use in audio devices that have closely-spaced speakers. In particular, crosstalk filtering as implemented in the circuit assumes that the external head-related contralateral filters are time-delayed and attenuated versions of the external, head-related ipsilateral filters. With this assumption, the circuit's crosstalk filtering is configurable for varying audio characteristics, according to a small number of settable parameters. These parameters include configurable first and second attenuation parameters for cross-path signal attenuation, and configurable first and second delay parameters for cross-path delay. Optional sound normalization, if included, uses similar simplified parameterization. Further, in one or more embodiments, the audio processing circuit and method include or are associated with a defined table of parameters that are least-squares optimized solutions. The optimized parameter values provide wider listening sweet spots for a greater variety of listeners.