Automated medical diagnostic interpretation and report generation for a non-invasive medical diagnostic test, such as an echo cardiogram, is provided. Various dimension measurements and physiological measurements from an echo cardiogram machine are transferred automatically to a computer over an echo cardiogram machine interface. The dimensions and physiological measurements are automatically interpreted by an intelligent interpretation engine running on a computer, generating various machine evaluations. The physician can approve the machine evaluations, overrule them, or make appropriate adjustments. Upon completion of the physician's review, the physician approved interpretations become diagnostic conclusions, and the report containing the results of the physician's review is generated by the report generation engine.