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US08295907B2 Integrated finite element and circulatory model for predicting hemodynamic effects of left ventricular impairment, resynchronization and remodeling 有权
综合有限元和循环模型预测左心室损伤,再同步和重塑的血液动力学影响

Integrated finite element and circulatory model for predicting hemodynamic effects of left ventricular impairment, resynchronization and remodeling
Abstract:
A computational model which integrates a complex circulatory model and a finite element to determine the dynamics of a left ventricle continuously over consecutive cardiac cycles. The model includes determining a LV pressure (plv) using a circulatory model, using a finite element model plv as input and determining a LV volume (vlv), computing a LV elastance according to: elv=plv/vlv, driving the circulatory model with the elv; and returning to determining a LV pressure and starting the next iteration, wherein the steps continue at a sufficient time resolution for a desired number of entire cardiac cycles. The dynamic Young's modulus functions are assigned to individual finite elements, resulting in a time-varying left ventricular elastance that drives the circulatory model.
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