Invention Grant
US08298567B2 Hyperbranched polyurea delivery system for binding and release of growth factors 失效
用于结合和释放生长因子的超支化聚脲递送系统

  • Patent Title: Hyperbranched polyurea delivery system for binding and release of growth factors
  • Patent Title (中): 用于结合和释放生长因子的超支化聚脲递送系统
  • Application No.: US12764887
    Application Date: 2010-04-21
  • Publication No.: US08298567B2
    Publication Date: 2012-10-30
  • Inventor: Jin Hu
  • Applicant: Jin Hu
  • Applicant Address: US MI Midland
  • Assignee: Michigan Molecular Institute
  • Current Assignee: Michigan Molecular Institute
  • Current Assignee Address: US MI Midland
  • Agency: Technology Law PLLC
  • Agent Karen L. Kimble
  • Main IPC: A61F2/02
  • IPC: A61F2/02
Hyperbranched polyurea delivery system for binding and release of growth factors
Abstract:
The present invention provides a polymer delivery system for the in vivo binding and release of growth factors, preferably orthobiologic GF, comprising a hyperbranched polymer having physiologically-acceptable anionic phosphorous groups. The hyperbranched polymer is preferred to be a polyurea with phosphonate anions. This polymer can be cross-linked to form a network and provide a coating for implanted devices.
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