A communication device cognitively monitors interference signals across a communication band so that adaptations for physical and medium access control (MAC) of data packet transmissions are appropriate for a particular interference signal. Characteristics of an interference signal of interest (e.g., bandwidth, power and/or duration relative to an average data packet transmitted over a communication channel of the communication device) are sensed for an appropriate adaptation (e.g., forward error correction, modulation technique, back off, request to send/clear to send protocol, etc.). Patterns for known types of interference sources can be compared so that when recognized an associated adaptation can be used.