The present disclosure provides a refrigerator having a cabinet including at least one access area having an open face and a grill door for selectively closing the open face of the access area. The refrigerator can also include a water using accessory provided on the cabinet. The grill door can be selectively retained to the cabinet wherein a manifold is fixed relative to the grill door and fluidly couples the water using accessory to a water supply. A water treatment cartridge can be removably coupled to a casing such that when the cartridge is coupled to the manifold, the cartridge treats the water from the water supply for use by the water using accessory. The manifold can be located on the grill door such that the mounting of the cartridge to the manifold moves the cartridge from within the access area to outside of the access area as the grill door moves from a closed position to an opened position, respectively.