Invention Grant
US08304235B2 Nucleic acid codifying for a utrophin transcription specific regulating protein, protein codified thereby and uses thereof
有权
编码utrophin转录特异性调节蛋白的核酸,由此编码的蛋白质及其用途
- Patent Title: Nucleic acid codifying for a utrophin transcription specific regulating protein, protein codified thereby and uses thereof
- Patent Title (中): 编码utrophin转录特异性调节蛋白的核酸,由此编码的蛋白质及其用途
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Application No.: US12680681Application Date: 2008-10-06
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Publication No.: US08304235B2Publication Date: 2012-11-06
- Inventor: Claudio Passananti , Nicoletta Corbi , Annalisa Onori , Maria Grazia Di Certo
- Applicant: Claudio Passananti , Nicoletta Corbi , Annalisa Onori , Maria Grazia Di Certo
- Applicant Address: IT Rome
- Assignee: CNR- Consiglio Nazionale Delle Ricerche
- Current Assignee: CNR- Consiglio Nazionale Delle Ricerche
- Current Assignee Address: IT Rome
- Agency: Lucas & Mercanti, LLP
- Priority: ITRM2007A0523 20071005
- International Application: PCT/IB2008/054089 WO 20081006
- International Announcement: WO2009/044383 WO 20090409
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C07H21/02 ; C07K14/00

Abstract:
The present invention relates to a nucleic acid molecule comprising a nucleotide sequence codifying for a protein characterized in having at least four zinc finger domains and in modulating the transcription of the utrophin gene by binding to a nucleotidic sequence comprised in a utrophin gene untranscribed regulatory sequence. Protein codified thereby and uses thereof.
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