A method and apparatus for performing computed tomography in medical imaging through reconstruction of a data set containing projections obtained during relative motions a container or body of interest with respect to an x-ray source and/or x-ray detector panel. Strobing of the data is implemented through one or more methods to include pulsing of the x-ray source, intermittent blanking of the x-ray detector panel, or intermittent processing of data collected from the detector panel to simulate blanking. The invention is utilized to significantly improve contrast by taking advantage of the pulsed nature of the source to implement three-dimensional reconstruction.