A system and method for obtaining a quantitative measurement of the location and size of a contrast material within a bodily organ, such as the GI tract of a person. A contrast material is introduced into the organ and a plurality of images is obtained. A curve representing the bodily organ is formed based on the images. Local image fields are defined along the curve and a field intensity is found for each by integrating the intensity of the image in the field. An intensity profile along the length of the curve is thus obtained for each image and provides a quantitative representation of contrast material along the bodily organ. The profiles are displayed in any suitable way. In some embodiments, identification of the curve may be aided by introduction of targets are into the organ. The target locations can be identified in each image. In some embodiments, an image obtained without the contrast material is subtracted from each of the plurality of images to cancel the background radiopacity and isolate the contrast material in each profile.