A system and method is provided for thruster control in a flight vehicle. The system and method uses a proportional derivative matrix control technique to determine thrust commands in a Divert and Attitude control (DAC) system. The proportional derivative matrix control system is configured to receive pitch, roll and yaw commands as inputs, and generate thrust commands as outputs. The performance of the proportional derivative matrix controller is such that the thrust commands can achieve the desired attitude angles quickly and with reduced fuel consumption. The matrix control system can efficiently control a variety of thrusters, including asymmetric thrusters having different moment arms. The matrix control system is particularly suitable to the control of DAC systems with asymmetric thrusters that are configured for attitude control.