A system and method for assisting printed circuit board design are characterized by a circuit pre-configuration interface capable of synchronously performing circuit design and performing pre-configuration layout of electronic parts in the circuitry to thereby solve a known problem, wherein engineers spend considerable time arranging electronic parts at a late stage due to layout engineers' unfamiliarity with a circuit's characteristics. The circuit pre-configuration interface also directly adjusts and modifies electronic parts in the finalized circuitry, thereby providing a data exchange platform for the circuit design software and circuit layout software to increase the circuit layout efficiency.