Example methods and apparatus to dynamically optimize platforms are disclosed. A disclosed example method includes configuring a processor to operate in a first mode, executing a workload on the processor, and sampling a plurality of registers associated with a performance monitoring unit (PMU). The example method also includes transforming the sampled plurality of registers into a Gaussian signal, partitioning the probabilistic model representation into a plurality of discrete output symbols, and associating one of the plurality of discrete output symbols with the workload based on a probability value associated with the one of the plurality of discrete output symbols.