Invention Grant
US08323654B2 Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules
有权
与含唾液酸的分子结合的抗淀粉样蛋白β抗体
- Patent Title: Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules
- Patent Title (中): 与含唾液酸的分子结合的抗淀粉样蛋白β抗体
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Application No.: US12788116Application Date: 2010-05-26
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Publication No.: US08323654B2Publication Date: 2012-12-04
- Inventor: Michael E. Benz , Lisa L. Shafer , Deepak R. Thakker
- Applicant: Michael E. Benz , Lisa L. Shafer , Deepak R. Thakker
- Applicant Address: US MN Minneapolis
- Assignee: Medtronic, Inc.
- Current Assignee: Medtronic, Inc.
- Current Assignee Address: US MN Minneapolis
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/70 ; A61K31/7028 ; A61K31/7032 ; C12P21/08 ; C07K16/18 ; A61M31/00
Abstract:
Antibody complexes including anti-Aβ antibodies conjugated with a sialic acid-containing molecule show improved bioavailability with no significant adverse effects on binding to amyloid beta.
Public/Granted literature
- US20110202000A1 ANTI-AMYLOID BETA ANTIBODIES CONJUGATED TO SIALIC ACID-CONTAINING MOLECULES Public/Granted day:2011-08-18
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