Invention Grant
- Patent Title: Substituted piperazines
- Patent Title (中): 取代的哌嗪
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Application No.: US12555650Application Date: 2009-09-08
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Publication No.: US08324216B2Publication Date: 2012-12-04
- Inventor: Andrew M. K. Pennell , James B. Aggen , J. J. Kim Wright , Subhabrata Sen , Brian E. McMaster , Daniel Joseph Dairaghi , Wei Chen , Penglie Zhang
- Applicant: Andrew M. K. Pennell , James B. Aggen , J. J. Kim Wright , Subhabrata Sen , Brian E. McMaster , Daniel Joseph Dairaghi , Wei Chen , Penglie Zhang
- Applicant Address: US CA Mountain View
- Assignee: Chemocentryx, Inc.
- Current Assignee: Chemocentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D233/61 ; C07D249/14 ; C07D257/04
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20100240618A1 SUBSTITUTED PIPERAZINES Public/Granted day:2010-09-23
Information query
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