Invention Grant
- Patent Title: Substituted thieno [2,3-d] pyrimidines as HIV inhibitors
- Patent Title (中): 取代噻吩并[2,3-d]嘧啶作为HIV抑制剂
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Application No.: US13470119Application Date: 2012-05-11
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Publication No.: US08324223B2Publication Date: 2012-12-04
- Inventor: Jean-Luc Girardet , Zhi Hong , Stephanie Shaw , Yung-hyo Koh
- Applicant: Jean-Luc Girardet , Zhi Hong , Stephanie Shaw , Yung-hyo Koh
- Applicant Address: US CA San Diego
- Assignee: Ardea Biosciences, Inc.
- Current Assignee: Ardea Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/519 ; A61P31/18
![Substituted thieno [2,3-d] pyrimidines as HIV inhibitors](/abs-image/US/2012/12/04/US08324223B2/abs.jpg.150x150.jpg)
Abstract:
This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.
Public/Granted literature
- US20120225894A1 Substituted Thienol[2,3-d] pyrimidines as HIV Inhibitors Public/Granted day:2012-09-06
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