Invention Grant
US08324373B2 Highly stereoselective process for preparing gemcitabine and intermediates thereof
有权
制备吉西他滨及其中间体的高度立体选择性方法
- Patent Title: Highly stereoselective process for preparing gemcitabine and intermediates thereof
- Patent Title (中): 制备吉西他滨及其中间体的高度立体选择性方法
-
Application No.: US12601942Application Date: 2007-09-07
-
Publication No.: US08324373B2Publication Date: 2012-12-04
- Inventor: Yongxiang Xu , Hao Yang , Wen Hou
- Applicant: Yongxiang Xu , Hao Yang , Wen Hou
- Applicant Address: CN
- Assignee: Nanjing Cavendish Bio-Engineering Technology Co., Ltd.
- Current Assignee: Nanjing Cavendish Bio-Engineering Technology Co., Ltd.
- Current Assignee Address: CN
- Agency: Kolisch Hartwell, P.C.
- Priority: CN200710106089 20070531
- International Application: PCT/CN2007/002672 WO 20070907
- International Announcement: WO2008/144970 WO 20081204
- Main IPC: C07H19/00
- IPC: C07H19/00 ; C07H21/00 ; C07H1/00 ; C07H3/00 ; C08B37/00 ; A01N43/04 ; A61K31/70 ; C07D237/00 ; C07D237/02
Abstract:
The present invention provides a novel and highly stereoselective process for preparing gemcitabine, which is suitable for industrial production, wherein, it includes the following reactions. Additionally, the invention discloses the key intermediates. The definition for the groups of G1, G2, G3, G4, and G5 are described in the specification.
Public/Granted literature
- US20100179314A1 Novel and Highly Stereoselective Process for Preparing Gemcitabine and Intermediates Thereof Public/Granted day:2010-07-15
Information query
