Invention Grant
- Patent Title: Chimeric avian-based screening system containing mammalian grafts
- Patent Title (中): 基于嵌合体的哺乳动物筛选系统
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Application No.: US11571343Application Date: 2005-06-28
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Publication No.: US08324447B2Publication Date: 2012-12-04
- Inventor: Ron Goldstein , Tamar Tennenbaum , Varda Deutsch
- Applicant: Ron Goldstein , Tamar Tennenbaum , Varda Deutsch
- Applicant Address: IL Ramat Gan IL Tel-Aviv
- Assignee: Bar Ilan University,Medical Research Fund of Tel-Aviv Sourasky Medical Center
- Current Assignee: Bar Ilan University,Medical Research Fund of Tel-Aviv Sourasky Medical Center
- Current Assignee Address: IL Ramat Gan IL Tel-Aviv
- Agency: Booth Udall, PLC
- Agent Rodney J. Fuller
- International Application: PCT/IL2005/000687 WO 20050628
- International Announcement: WO2006/001021 WO 20060105
- Main IPC: A01K67/00
- IPC: A01K67/00 ; A01K67/027 ; G01N33/00 ; C12N5/00

Abstract:
The present invention relates to animal model systems comprising a chimera between an avian embryo and a mammalian organism. Specifically, chimeric model systems comprising normal, diseased or genetically transformed mammalian cells and tissues transplanted into avian embryos, and uses thereof for in vivo testing of drugs and therapeutic modalities are disclosed.
Public/Granted literature
- US20090064349A1 Chimeric Avian-Based Screening System Containing Mammalian Grafts Public/Granted day:2009-03-05
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