Invention Grant
US08326412B2 Diagnostic device and method for sensing hydration state of a mammalian subject
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用于感测哺乳动物受试者的水合状态的诊断装置和方法
- Patent Title: Diagnostic device and method for sensing hydration state of a mammalian subject
- Patent Title (中): 用于感测哺乳动物受试者的水合状态的诊断装置和方法
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Application No.: US13249521Application Date: 2011-09-30
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Publication No.: US08326412B2Publication Date: 2012-12-04
- Inventor: Andrew S. Goldstein , Frank Bellizzi
- Applicant: Andrew S. Goldstein , Frank Bellizzi
- Applicant Address: US CA Altadena
- Assignee: HydraDx, Inc.
- Current Assignee: HydraDx, Inc.
- Current Assignee Address: US CA Altadena
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Agent Vincent K. Gustafson
- Main IPC: A61B5/05
- IPC: A61B5/05

Abstract:
Timed sensing of collection of saliva in a liquid collection element of predetermined volumetric capacity may be used to determine salivary secretion rate, as may be indicative of state of euhydration or dehydration. Sensing of salivary flow rate may be further augmented by sensing concentration of at least one analyte in saliva (e.g., with an immunochromatographic assay performed in a lateral flow device) in order to determine a state of euhydration or dehydration. Production of saliva may be stimulated, and collected saliva may be analyzed to generate an analyte detection signal that indicative of presence and/or correlative of concentration of at least one analyte in the collected saliva to sense a state of euhydration or dehydration.
Public/Granted literature
- US20120083711A1 DIAGNOSTIC DEVICE AND METHOD FOR SENSING HYDRATION STATE OF A MAMMALIAN SUBJECT Public/Granted day:2012-04-05
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