The disclosure is related to data storage systems having multiple cache and to management of cache activity in data storage systems having multiple cache. In a particular embodiment, a data storage device includes a volatile memory having a first read cache and a first write cache, a non-volatile memory having a second read cache and a second write cache and a controller coupled to the volatile memory and the non-volatile memory. The memory can be configured to selectively transfer read data from the first read cache to the second read cache based on a least recently used indicator of the read data and selectively transfer write data from the first write cache to the second write cache based on a least recently written indicator of the write data.