Invention Grant
- Patent Title: Method for enhancing efficacy of preparation of monoclonal antibody
- Patent Title (中): 增强单克隆抗体制备功效的方法
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Application No.: US10546293Application Date: 2004-02-18
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Publication No.: US08332159B2Publication Date: 2012-12-11
- Inventor: Toshio Murakami , Hirofumi Higuchi , Keiichi Makizumi , Toshihiro Maeda , Hiroshi Mizokami
- Applicant: Toshio Murakami , Hirofumi Higuchi , Keiichi Makizumi , Toshihiro Maeda , Hiroshi Mizokami
- Applicant Address: JP Kumamoto-Ken
- Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- Current Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- Current Assignee Address: JP Kumamoto-Ken
- Agency: Browdy and Neimark, P.L.L.C.
- Priority: JP2003-042819 20030220
- International Application: PCT/JP2004/001822 WO 20040218
- International Announcement: WO2004/074516 WO 20040902
- Main IPC: G06F7/00
- IPC: G06F7/00
Abstract:
A method of enhancing the efficacy of a monoclonal antibody preparation wherein antigens from patients are tested for their reactivity with the antibody. An amino acid sequence of an expressed protein is deuced from a nucleotide sequence determined by isolation and analysis of a target molecule gene in a biopsy from a patient. This is compared with the previously determined amino acid sequence recognized by the monoclonal antibody preparation in order to assess the fitness of patients for administration of the monoclonal antibody preparation.
Public/Granted literature
- US20060280751A1 Method for enhancing efficacy of preparation of monoclonal antibody Public/Granted day:2006-12-14
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