Invention Grant
- Patent Title: Process for producing imidazo[1,2-b]pyridazine compound
- Patent Title (中): 咪唑并[1,2-b]哒嗪化合物的制备方法
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Application No.: US12064832Application Date: 2006-08-22
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Publication No.: US08334379B2Publication Date: 2012-12-18
- Inventor: Ichiro Komoto , Kazuaki Sasaki , Tomohiko Gotou
- Applicant: Ichiro Komoto , Kazuaki Sasaki , Tomohiko Gotou
- Applicant Address: JP Tokyo
- Assignee: Sumitomo Chemical Company, Limited
- Current Assignee: Sumitomo Chemical Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: JP2005-248845 20050830
- International Application: PCT/JP2006/316790 WO 20060822
- International Announcement: WO2007/026621 WO 20070308
- Main IPC: C07D487/00
- IPC: C07D487/00
![Process for producing imidazo[1,2-b]pyridazine compound](/abs-image/US/2012/12/18/US08334379B2/abs.jpg.150x150.jpg)
Abstract:
A process for producing an imidazo[1,2-b]pyridazine compound represented by the formula (2): wherein R1, R2 and R3 are the same or different and each represents a hydrogen atom, a halogen atom, an alkyl group which may be substituted with a halogen atom or atoms, an alkenyl group which may be substituted with a halogen atom or atoms, or an alkoxy group which may be substituted with a halogen atom or atoms, which comprises reacting a 2,3-dihydropyridazine compound represented by the formula (1): wherein R1, R2 and R3 are the same meanings as defined above, with a phosphorus oxyhalide in the presence of an organic base which is in an amount of 0.5 mole or more relative to 1 mole of the 2,3-dihydropyridazine compound and 1 mole or less relative to 1 mole of the phosphorus oxyhalide.
Public/Granted literature
- US20100234597A1 PROCESS FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND Public/Granted day:2010-09-16
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