A method and apparatus for cross-talk resistant adaptive noise cancellation. The method includes retrieving, via the processor, a primary signal and a reference signal, filtering the primary signal utilizing a filter H12(z) and estimating a cross-talk, filtering the reference signal utilizing a filter H21(z) and estimating the noise leakage of the reference signal, determining the difference between the noise leakage estimate from the primary signal and estimating a first post-filtering, determining the difference between the cross-talk estimate and the reference signal and estimating a second post-filtering, determining if the voice activity is detected in the primary signal, adapting filters H12 and H21 by de-correlation if the voice activity is detected, and adapting filter H12 by NLMS if the voice activity is not detected, limiting maximum filter change during different conditions for protecting filters H12 and H21 from diverging, maintaining filter stability by tracking absolute sum of the coefficients of the convolution of H12 and H21, obtaining a primary output and a reference output utilizing the first post-filtering and the second post-filtering, and utilizing the primary output and the reference output for cross-talk resistant adaptive noise cancellation.