Invention Grant
- Patent Title: Anti-HIMF antibodies to treat lung diseases
- Patent Title (中): 用于治疗肺部疾病的抗HIMF抗体
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Application No.: US12518857Application Date: 2007-12-18
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Publication No.: US08343491B2Publication Date: 2013-01-01
- Inventor: Roger A. Johns , Qingning Su , Hunter Clay Champion
- Applicant: Roger A. Johns , Qingning Su , Hunter Clay Champion
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Johns Hopkins Technology Transfer
- International Application: PCT/US2007/087899 WO 20071218
- International Announcement: WO2008/077022 WO 20080626
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Hypoxia induced mitogenic factor (HIMF) is a member of the “found in inflammatory zone” (FIZZ)/resistin family of proteins and has potent mitogenic, angiogenic, and vasoconstrictive effects in the lung vasculature. We use antibodies to HIMF to treat certain diseases including adult respiratory distress syndrome, radiation-induced pulmonary fibrosis, idiopathic pulmonary fibrosis, and emphysema.
Public/Granted literature
- US20100028355A1 HIMF AND BTK IN PULMONARY, CARDIAC AND INFLAMMATION DISORDERS Public/Granted day:2010-02-04
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