Invention Grant
- Patent Title: Targeting of antigen presenting cells with immunonanotherapeutics
- Patent Title (中): 用免疫疗法靶向抗原呈递细胞
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Application No.: US12428381Application Date: 2009-04-22
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Publication No.: US08343497B2Publication Date: 2013-01-01
- Inventor: Jinjun Shi , Frank Alexis , Matteo Iannacone , Elliott Ashley Moseman , Pamela Basto , Robert S. Langer , Omid C. Farokhzad , Ulrich von Andrian , Elena Tonti
- Applicant: Jinjun Shi , Frank Alexis , Matteo Iannacone , Elliott Ashley Moseman , Pamela Basto , Robert S. Langer , Omid C. Farokhzad , Ulrich von Andrian , Elena Tonti
- Applicant Address: US MA Boston US MA Cambridge US MA Cambridge
- Assignee: The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,Massachusetts Institute of Technology
- Current Assignee: The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,Massachusetts Institute of Technology
- Current Assignee Address: US MA Boston US MA Cambridge US MA Cambridge
- Agency: Pabst Patent Group LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K47/00
Abstract:
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.
Public/Granted literature
- US20100129392A1 Targeting of Antigen Presenting Cells with Immunonanotherapeutics Public/Granted day:2010-05-27
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