Invention Grant
- Patent Title: Peptide composition
- Patent Title (中): 肽组成
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Application No.: US11979224Application Date: 2007-10-31
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Publication No.: US08343500B2Publication Date: 2013-01-01
- Inventor: David Cameron Wraith , Heather Barbara Streeter
- Applicant: David Cameron Wraith , Heather Barbara Streeter
- Applicant Address: GB Bristol
- Assignee: Apitope Technology (Bristol) Limited
- Current Assignee: Apitope Technology (Bristol) Limited
- Current Assignee Address: GB Bristol
- Agency: Marshall, Gerstein & Borun LLP
- Priority: GB0020618.5 20000821; GB0114547.3 20010614
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/00 ; A61K39/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00

Abstract:
There is provided a method for selecting a tolerogenic peptide by selecting a peptide which is capable of binding to an MHC class I or II molecule without further processing. There is also provided a peptide selected by such a method and its use in a pharmaceutical composition and a method to treat and/or prevent a disease. The present invention also relates to a composition which comprises the following myelin basic protein (MBP) peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154. The composition may be used to treat a disease, in particular multiple sclerosis and/or optical neuritis and the invention also relates to such uses and methods.
Public/Granted literature
- US20080200368A1 Peptide composition Public/Granted day:2008-08-21
Information query
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