Invention Grant
US08343514B2 Sol-gel nanostructured titania reservoirs for use in the controlled release of drugs in the central nervous system and method of synthesis
有权
用于中枢神经系统药物控制释放的溶胶 - 凝胶纳米结构二氧化钛储库和合成方法
- Patent Title: Sol-gel nanostructured titania reservoirs for use in the controlled release of drugs in the central nervous system and method of synthesis
- Patent Title (中): 用于中枢神经系统药物控制释放的溶胶 - 凝胶纳米结构二氧化钛储库和合成方法
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Application No.: US12303953Application Date: 2006-06-06
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Publication No.: US08343514B2Publication Date: 2013-01-01
- Inventor: Tessy Maria Lopez-Goerne
- Applicant: Tessy Maria Lopez-Goerne
- Applicant Address: MX Tlalpan
- Assignee: Universidad Autonome Metropolitana
- Current Assignee: Universidad Autonome Metropolitana
- Current Assignee Address: MX Tlalpan
- Agency: Browdy and Neimark, P.L.L.C.
- International Application: PCT/IB2006/001725 WO 20060606
- International Announcement: WO2007/141590 WO 20071213
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61F13/00 ; C22C14/00 ; C22C29/00

Abstract:
The invention is related to a sol-gel nanostructured titania reservoir and its synthesis which is biocompatible with brain tissue. The pore size distribution, crystallite size and the extent of the crystalline phase distribution of anatase, brookite and rutile can be fully controlled. This device may be used to contain neurological drugs. It may be inserted directly into brain tissue for the purpose of the controlled time release of drugs over a period of from 6 months to three years.
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